Anastrozole is an orally active medicine that is being used for treating breast cancer in women that have gone through the menopause period. The compound is helpful for treating hormonally positive breast cancer (the one that requires estrogen) and that’s because Anastrozole is an Aromatase Inhibitor (AI) that is lowering total estrogen levels in the body.
Anastrozole might be more familiar to you as the brand Arimidex – the most famous brand of Anastrozole as is the first one. However, it may also be found as other brands too – all of which are having the exact same dosage and active substance of the drug.
The compound is mostly used for treating breast cancer for women in medical settings but there may be other uses too. Nonetheless, we’re going to talk about “What is Anastrozole?” in bodybuilding settings.
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Anastrozole (Arimidex) for bodybuilders used for the same purpose – for lowering total estrogen levels in the body.
How Does Anastrozole Work?
Anastrozole (with brand Arimidex or any other) is working by binding to the aromatase enzymes and therefore blocking the estrogen formation. As a result, people using Anastrozole are reducing the total amount of estrogen made by the body.
There are specific health issues as well as some specific breast cancers that are being stimulated by the growth of the hormone estrogen. They are called ER+ (estrogen receptor positive) breast cancers.
- Since Anastrozole is an anti estrogen and more specifically an Aromatase Inhibitor (AIs) it binds to the aromatase enzymes and is blocking the formation of estrogen. By using the compound, you’re lowering the total amount of estrogen floating in the body.
Who Needs Anastrozole?
A short and quick answer would be: everyone who needs to lower estrogen levels.
However, if we think about it more broadly, then Anastrozole is mostly suitable for women who have been through the menopause and who suffers from ER+ breast cancer.
Nonetheless, there are also men, and mostly men using anabolic steroids that need Anastrozole too. That’s because steroids are boosting testosterone. A part of testosterone is converted into estrogen through aromatization. When running those steroids for a while, you get too much estrogen and that’s going to lead to various different negative effects and symptoms.
If you wish to continue using steroids to grow muscles, gain strength and for your general physique and performance enhancement purposes safely, you need to add some estrogenic protection during the cycle. And Anastrozole is considered one of the best and one of the most popular ones.
Therefore Anastrozole – Arimidex is used by male bodybuilders using aromatizable (wet) steroids and by women with breast cancer. There are other situations when a person may need to use Arimidex, but is still related to high estrogen issues.
- NOTE! Not all steroids aromatize. There’s no need to use Anastrozole in case you run a steroid that doesn’t convert into estrogen.
If you’re thinking of running Anastrozole for any health condition then we recommend using it exactly as recommended by the prescribing doctor. Do not use it in any other way. Doctors, however, won’t offer a dosing guideline for bodybuilding purposes.
That’s why we highly recommend you to use the compound very carefully. We recommend starting very slowly and increasing dosage only if needed.
You may start at 0.5 mg (half a tablet of Arimidex) taken every 2-3 days during your cycle. Slowly increase if you need, but you very rarely or never need more than 1 mg a day.
The dosage is highly dependent on the steroid dosage (level of aromatization).
Anastrozole Side Effects
The side effects of Anastrozole for men are almost nonexistent because you need to use it in real high doses to suppress estrogen way too much and that’s leading to various negative side effects.
Keep in mind that estrogen is needed by men (and especially women) for normal functioning.
Too high estrogen leads to side effects and symptoms which is why Arimidex is used.
But too low estrogen levels also have its own negative side effects and symptoms which occur when you use Anastrozole too aggressively.
Some side effects that can be mentioned include:
- Low libido
- Low energy levels
- Erectile dysfunction
- Mood and depression
- And various others
If you think about running anabolic steroids and you are wondering “what is Anastrozole?” then we consider that’s great!
Thanks to this, you are going to be prepared for estrogenic side effects and can control them or even prevent them altogether.
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